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Gerd R Burmester Selected Research

sarilumab

1/2022Sarilumab monotherapy vs sarilumab and methotrexate combination therapy in patients with rheumatoid arthritis.
11/2021Long-term safety and efficacy of sarilumab over 5 years in patients with rheumatoid arthritis refractory to TNF inhibitors.
10/2020Efficacy and safety of sarilumab in combination with csDMARDs or as monotherapy in subpopulations of patients with moderately to severely active rheumatoid arthritis in three phase III randomized, controlled studies.
1/2020Long-term safety of sarilumab in rheumatoid arthritis: an integrated analysis with up to 7 years' follow-up.
1/2020Association of High Serum Interleukin-6 Levels With Severe Progression of Rheumatoid Arthritis and Increased Treatment Response Differentiating Sarilumab From Adalimumab or Methotrexate in a Post Hoc Analysis.
1/2020EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2019 update.
1/2020Sarilumab and adalimumab differential effects on bone remodelling and cardiovascular risk biomarkers, and predictions of treatment outcomes.
1/2019Safety and efficacy of switching from adalimumab to sarilumab in patients with rheumatoid arthritis in the ongoing MONARCH open-label extension.
1/2019Long-term safety and efficacy of sarilumab plus methotrexate on disease activity, physical function and radiographic progression: 5 years of sarilumab plus methotrexate treatment.
1/2018Patient-reported outcomes from a randomized phase III trial of sarilumab monotherapy versus adalimumab monotherapy in patients with rheumatoid arthritis.
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Gerd R Burmester Research Topics

Disease

110Rheumatoid Arthritis
04/2022 - 05/2003
20Infections
04/2022 - 05/2008
16Necrosis
10/2020 - 06/2007
12Arthritis (Polyarthritis)
01/2020 - 08/2004
11Psoriatic Arthritis
04/2022 - 04/2005
11Rheumatic Diseases (Rheumatism)
01/2022 - 05/2010
11Inflammation (Inflammations)
01/2021 - 11/2004
11Autoimmune Diseases (Autoimmune Disease)
01/2020 - 05/2003
9Pain (Aches)
01/2022 - 10/2012
9Fatigue
01/2022 - 01/2006
8Herpes Zoster
04/2022 - 01/2018
7Ankylosing Spondylitis
01/2020 - 08/2009
7Systemic Scleroderma (Systemic Sclerosis)
01/2018 - 09/2008
6Neoplasms (Cancer)
04/2022 - 04/2013
6Chronic Disease (Chronic Diseases)
01/2022 - 10/2012
5Vasculitis (Vasculitides)
01/2022 - 05/2004
5Osteoarthritis
01/2021 - 08/2004
5Systemic Lupus Erythematosus (Libman-Sacks Disease)
10/2015 - 01/2006
4Connective Tissue Diseases (Connective Tissue Disease)
05/2022 - 01/2009
4Nasopharyngitis
04/2022 - 02/2013
4Psoriasis (Pustulosis Palmaris et Plantaris)
01/2021 - 04/2005
4Fibrosis (Cirrhosis)
01/2018 - 01/2009
3Respiratory Tract Infections (Respiratory Tract Infection)
04/2022 - 01/2018
3COVID-19
01/2022 - 01/2020
3Disease Progression
01/2020 - 03/2011
3Headache (Headaches)
01/2018 - 02/2013
3Injection Site Reaction
05/2017 - 11/2010
3Juvenile Arthritis (Juvenile Idiopathic Arthritis)
04/2013 - 04/2013
3digital ulcers
01/2009 - 09/2008
2Anemia
04/2022 - 08/2009
2Musculoskeletal Diseases (Musculoskeletal Disease)
01/2022 - 07/2017
2Ulcerative Colitis
01/2021 - 01/2020
2Urinary Tract Infections (Urinary Tract Infection)
01/2021 - 02/2013
2Skin Neoplasms (Skin Cancer)
01/2020 - 04/2013
2Interstitial Lung Diseases (Interstitial Lung Disease)
01/2020 - 01/2009
2Crohn Disease (Crohn's Disease)
01/2020 - 04/2013
2Melanoma (Melanoma, Malignant)
01/2020 - 04/2013
2Nausea
01/2018 - 02/2013
2Pulmonary Arterial Hypertension
10/2014 - 01/2009
2Contracture
01/2009 - 01/2009
2Ulcer
09/2008 - 08/2004

Drug/Important Bio-Agent (IBA)

25Antirheumatic Agents (DMARD)IBA
04/2022 - 04/2005
25Methotrexate (Mexate)FDA LinkGeneric
02/2022 - 01/2009
18Adalimumab (Humira)FDA Link
04/2022 - 06/2007
15Biological ProductsIBA
04/2022 - 05/2009
15tocilizumab (atlizumab)FDA Link
01/2020 - 05/2011
14CytokinesIBA
05/2022 - 09/2003
12Biomarkers (Surrogate Marker)IBA
05/2022 - 06/2007
12sarilumabIBA
01/2022 - 01/2017
10Abatacept (Orencia)FDA Link
01/2020 - 01/2014
9Janus Kinase InhibitorsIBA
04/2022 - 02/2013
9tofacitinibIBA
02/2022 - 02/2013
8AutoantibodiesIBA
01/2021 - 05/2003
8Monoclonal AntibodiesIBA
01/2018 - 09/2011
7Rituximab (Mabthera)FDA Link
01/2022 - 08/2009
7GlucocorticoidsIBA
01/2021 - 01/2016
7Interleukin-6 (Interleukin 6)IBA
01/2020 - 01/2009
7Pharmaceutical PreparationsIBA
01/2020 - 07/2012
7AntibodiesIBA
01/2018 - 05/2004
6GLPG0634IBA
04/2022 - 01/2020
6Tumor Necrosis Factor InhibitorsIBA
11/2021 - 05/2011
6ametantrone (HAQ)IBA
01/2018 - 10/2012
6Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2018 - 09/2003
5upadacitinibIBA
04/2022 - 12/2016
5AntigensIBA
01/2022 - 11/2006
5Etanercept (Enbrel)FDA Link
01/2021 - 05/2009
5InterleukinsIBA
01/2020 - 04/2007
5AutoantigensIBA
01/2020 - 05/2003
5Infliximab (Remicade)FDA Link
01/2020 - 04/2005
5mavrilimumabIBA
01/2018 - 09/2011
4omega-Chloroacetophenone (Mace)IBA
04/2022 - 01/2019
4Interleukin-6 Receptors (Interleukin 6 Receptor)IBA
10/2020 - 04/2013
4golimumabFDA Link
01/2020 - 01/2018
4Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA
01/2018 - 09/2011
3Immunoglobulins (Immunoglobulin)IBA
05/2022 - 05/2008
3ChemokinesIBA
05/2022 - 05/2004
3baricitinibIBA
01/2022 - 01/2019
3Leflunomide (Arava)FDA LinkGeneric
11/2021 - 01/2018
3Indocyanine Green (Cardio-Green)FDA LinkGeneric
01/2021 - 04/2012
3Certolizumab PegolFDA Link
01/2020 - 01/2009
3Biosimilar PharmaceuticalsIBA
01/2020 - 03/2013
3Sulfasalazine (Azulfidine)FDA LinkGeneric
01/2020 - 07/2012
3C-Reactive ProteinIBA
01/2017 - 08/2009
3Rheumatoid FactorIBA
05/2016 - 05/2004
2vinyltriethoxysilane (VTES)IBA
04/2022 - 01/2021
2Creatine Kinase (Creatine Phosphokinase)IBA
04/2022 - 01/2021
2Interferon Type IIBA
01/2022 - 08/2017
2VaccinesIBA
01/2022 - 01/2022
2Hydroxychloroquine (Plaquenil)FDA LinkGeneric
01/2021 - 10/2014
2Immunoglobulin G (IgG)IBA
01/2021 - 01/2006
2Immunologic Factors (Immunomodulators)IBA
01/2021 - 02/2013
2Phosphotransferases (Kinase)IBA
01/2021 - 01/2012
2acetyl 4-aminosalicylic acidIBA
01/2020 - 07/2017
2Toll-Like Receptors (Toll-Like Receptor)IBA
01/2020 - 05/2004
2EpitopesIBA
01/2020 - 01/2018
2Granulocyte-Macrophage Colony-Stimulating Factor Receptors (GM-CSF Receptor)IBA
06/2017 - 09/2011
2AngiotensinsIBA
10/2014 - 03/2011
2Endothelins (Endothelin)IBA
10/2014 - 03/2011

Therapy/Procedure

37Therapeutics
01/2022 - 11/2004
2Drug Tapering
01/2020 - 01/2018